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Diethylcarbamazine citrate (DEC) works by targeting the microfilariae, which are the larval form of certain parasitic worms that cause diseases like lymphatic filariasis and tropical eosinophilia. DEC disrupts the metabolism of these microfilariae, leading to their paralysis and eventual death. This action helps to reduce the number of circulating microfilariae in the body, thereby alleviating symptoms and preventing the spread of the parasite. DEC is also believed to have anti-inflammatory effects, which can be beneficial in managing the immune response associated with these infections.
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